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[3] However, the precise contribution of each receptor pathway to gastrointestinal tolerability in a triple agonist has not been fully characterised in humans, and this attribution should be regarded as informed by class-effect data rather than confirmed mechanism

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Calcitonin gene-related peptide affects synaptic and membrane properties of bronchial parasympathetic neurons

downregulation) is a clear potential limiting factor in the capacity of a cell to generate prolonged signalling responses in the face of chronic ligand exposure