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This coverage gap is why telehealth compounded GLP-1 platforms have grown rapidly - they fill a need for patients who meet clinical criteria but can't afford out-of-pocket costs for brand-name medications without insurance coverage

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Several studies have tested GLP-1 and combination medications for people with MASLD who have not yet progressed to MASH and have little or no fibrosis Another dual GLP-1/glucagon agonist, pemvidutide, reduced liver fat content by up to 69% in people with MASLD and no significant fibrosis, compared with 4% in the placebo group, and more than half achieved normal liver fat levels

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