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It adds that patients with type 2 diabetes should be monitored for hypoglycemia when either agent is added to insulin or a sulfonylurea, and that a qualified provider must decide whether either medication is appropriate at all

Proc Natl Acad Sci U S A 107(11):52085213

That matters because GLP-1 progress is rarely linear

"This study theorizes that this may be due to suspected physiological stress, which may be a symptom of such rapid weight loss." Long-term hair loss seems to be more unlikely, the doctor said, as the "inciting event" (weight loss and stress) often normalizes as individuals reach their target weight

What dosing frequencies are used in research studies