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Long-term exposure to loud noise, whether at work or during leisure activities (eg, listening to loud music, live or through headphones), is well known to increase the chance of developing tinnitus, but evidence also shows even a single exposure to extremely loud noise, such as during military combat, can cause chronic tinnitus

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Journal of Endocrinology and Metabolism

Fatigue or drowsiness Due to its role in regulating melatonin and circadian rhythms, some may feel more tired initially

If semaglutide or tirzepatide produce significant weight loss that you maintain, the health benefits (reduced diabetes risk, improved cardiovascular health, better mobility) provide substantial long-term value