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Currently, no medications are approved for obesity treatment in children younger than 12 years, but a randomized controlled trial of 82 patients 6 to 12 years of age found that liraglutide resulted in an estimated BMI reduction of 7% compared with placebo, suggesting potential future applications
Heise T, De Vries JH, Coskun T, Urva S, Li J, Pratt EJ, Thomas MK, Mather KJ, Dunn JP, Haupt A, et al
That matters because the two compounds work through completely different pathways, and the safety data we have on AOD-9604 alone is already thin
While the primary goal is to boost NAD+ levels, this cascade could theoretically lead to unforeseen interactions with other metabolic pathways or even pharmacological agents being studied concurrently
Effects of liraglutide versus placebo on cardiovascular events in patients with type 2 diabetes mellitus and chronic kidney disease: Results from the LEADER trial
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