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Three models were constructed: Model 1 (crude model), Model 2 (adjusted for age and sex), and Model 3 (fully adjusted for potential confounders including BMI, blood pressure, lipid profile, renal function, osteocalcin (OCN), vitamin D levels, HbA1c, statin use, antihypertensive medication use, and smoking status)

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The second group (liraglutide, dulaglutide and semaglutide) have a modified human GLP-1 structure and, hence, a much closer homology to that of GLP-1 itself

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However, Gipr Syn/ mice had reduced total plasma cholesterol, regardless of treatment, compared to vehicle-treated Gipr fl/fl control mice (Extended Data Fig

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In-person consultations can take place at our clinic " Halo Health, 16 Station Road, Knowle, Solihull, B93 0HT " by appointment, providing a personalised and private clinical environment

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