We have reviewed previously the mechanistic explanations of how these multiple IO&NS pathways cause neuroaffective toxicity and, consequently, the onset of chronic fatigue syndrome and somatic and affective symptoms [28, 31, 81, 112,113,114]
Recent pharmacovigilance has also identified signals for intestinal obstruction (ileus) with some GLP-1 receptor agonists
GLP-1 medications are (at least so far) approved for long-term use
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The GLP-1 hormone tells the brain when the body is full earlier as a result of eating