Some people lose weight at a fraction of the rate seen in clinical trials and still achieve meaningful total loss over a longer timeframe
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Combination Therapy Use of Semaglutide in Patients with Type 2 Diabetes Mellitus Combination with Metformin and/or Thiazolidinediones In a 56-week, double-blind trial (NCT01930188), 1231 patients with type 2 diabetes mellitus were randomized to semaglutide 0.5 mg once weekly, semaglutide 1 mg once weekly, or sitagliptin 100 mg once daily, all in combination with metformin (94%) and/or thiazolidinediones (6%)
Williams, a 23-time Grand Slam champion, told Elle magazine that after having her second child in 2023, she lost weight within two weeks, but no matter what she did after that, she couldnt lose more