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Single nucleotide variants (SNVs) in the CYP, ABC , GST , ERC, and XPCC gene families may contribute to interindividual variations in drug toxicity [63,64,65,66,67,68]

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For many companies, the safest path is to exit GLP-1 sales and refocus on compounds with lower regulatory and IP risk

Permeability of the blood-brain barrier predicts no evidence of disease activity at 2 years after natalizumab or fingolimod treatment in relapsing-remitting multiple sclerosis

CXXC5 tips this balance toward inhibition