Berner TO, Murphy MM, Slesinski R
Remarkably, the charge distribution and shape of TrxR1 in this site is different with respect to TGR 33 due to the presence of charged and bulky residues, i.e., E337, D338, E341, E368 and K389 in human TrxR1 in place of A436, G437, Q440, S467 and D488 in TGR
Symptoms of SNHL include difficulty hearing soft sounds, distorted high-frequency sounds (s or th), trouble following speech (especially in noise), and tinnitus
There were also significant improvements in waist circumference, HgbA1c, fasting glucose, c-reactive protein, and fasting lipid levels
10.1161/CIRCRESAHA.118.312673 140 PalalauA
Alberti A, Pirrone P, Elia M, Waring RH, Romano C