Annual Review of Public Health 27:1-28
Ptriacq, P., Ton, J., Patrit, O., Tcherkez, G., & Gakire, B
became the worlds most profitable drug market This is why a drug that costs $245$350/month to make, distribute, and profit from ended up costing patients $1,000+
The table below shows the current list price, the price after applying code KLIKOOGQWG , and the resulting cost per milligram
J Biol Chem 277(38):3503535043 DeYoung MB, MacConell L, Sarin V, Trautmann M, Herbert P (2011) Encapsulation of exenatide in poly-(D, L-lactide-co-glycolide) microspheres produced an investigational long-acting once-weekly formulation for type 2 diabetes
While theyre fundamentally similar medications, they differ slightly in their mechanism of action: Wegovy (semaglutide) is a GLP-1 agonist Zepbound (tirzepatide) is a dual agonist: GLP-1 + a glucose-dependent insulinotropic polypeptide (GIP) Both semaglutide and tirzepatide affect the hypothalamus and the hedonic eating centers, the brains center of appetite and cravings