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HO-1 induction by CO-RM2 attenuates TNF-alpha-induced cytosolic phospholipase A2 expression via inhibition of PKCalpha-dependent NADPH oxidase/ROS and NF-kappaB
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We found that in the gld-2 gld-1 double null mutant, LAG-1 level was elevated ~4.5-fold, as assessed at 25 cd from the distal tip
That said, individual outcomes can vary
But McCullough doesn't have cardiovascular disease and wouldn't qualify
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