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The most common causes include hypoglycemia (especially when combined with insulin or sulfonylureas), gastrointestinal distress triggering vasovagal responses, dehydration from GI side effects, or anxiety related to treatment

Abstract Background Oxidative stress has been identified in the peritoneal fluid and peripheral blood of women with endometriosis

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Velmurugan et al

iTRAQ-based proteomics implies inflammasome pathway activation in the prefrontal cortex of CSDS mice may influence resilience and susceptibility

Several important safety considerations from UK SmPCs include: Pancreatitis risk : Seek immediate medical attention for severe, persistent abdominal pain Gallbladder disease : Including cholelithiasis and cholecystitis Diabetic retinopathy complications : Particularly with semaglutide in those with pre-existing retinopathy Dehydration and acute kidney injury : Possible with severe gastrointestinal side effects Hypoglycaemia : Increased risk when used with insulin or sulfonylureas (dose adjustment of these medications may be needed) Pregnancy/breastfeeding : Weight management GLP-1 agonists (Wegovy, Saxenda) are contraindicated in pregnancy and should be avoided during breastfeeding [5] [2] Regarding mental health specifically, regulatory agencies have scrutinised GLP-1 medications for potential psychiatric adverse effects