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As the melanosis score increased, the number of affected segments increased, and the number of patients decreased

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Cardiac-specific SIRT2 overexpression causes a reduction in mTOR activity and protein synthesis in mice hearts Next, to understand if cardiac-specific overexpression of SIRT2 can reduce protein synthesis in these mice hearts, we developed cardiac-specific SIRT2 overexpressing (csSIRT2-Tg) mice (Fig

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