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While a number of the genes identified are outside of the identified GLP-1RA MoA and not highlighted in the literature, several genes identified in this analysis are known to modulate GLP-1 signaling or mediate shared clinical outcomes

Obesity 0, 1 to 4

0:33:15.8 ET: Great question

doi:10.1002/phar.2688 67

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Future Potential : The robust pipeline of increasingly effective agents, combined with emerging oral formulations and potential cost reduction strategies, suggests that current limitations may be surmountable with continued innovation and policy development