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IGF-1 activates the PI3K-Akt-mTOR pathway in muscle satellite cells, driving their proliferation and differentiation into new myofibers

However, macrophages in aged organisms exhibit several functional impairments, which contribute to a weakened immune system and increased susceptibility to inflammation and infection

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doi: 10.1016/j.clnesp.2021.11.017 194 MalkawiRJarwanBWaleedRYounisR