Discontinuations of one or two years without resuming GLP-1 use resulted in a 14% or 22% increased risk of cardiovascular events, respectively, compared to staying on the drugs
Cardiovasc Res (2023) 118(17):327287
Semaglutide 2.4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial
The peptide research community benefits collectively when researchers share their evaluation findings, helping others identify quality sources more efficiently
However, for metabolically healthy women considering GLP-1s for modest weight loss, the risks may outweigh the benefits
Neurogastroenterology Motil 21(6):609e22 Hellstrm PM, Nslund E, Edholm T, Schmidt PT, Kristensen J, Theodorsson E, Efendic S (2008) GLP-1 suppresses Gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome