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RNA-seq analysis was performed using three biological replicates per condition ( b, c )

Over time, high blood sugar can impair blood vessels, reducing blood flow to the scalp and hair follicles and potentially limiting the nutrients needed for healthy hair growth

To identify the treatment cohort, the KRD was searched for all patients with 1 claim for semaglutide 2.4 mg between June 15, 2021 and July 31, 2022

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In addition, GLP-1R stimulation activates insulin signaling pathways and regulates gene expression, decreasing systemic insulin resistance and brain insulin resistance in patients with AD (Dahiya et al., 2025)

It mimics a natural hormone that reduces appetite, improves blood sugar, and slows digestion