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Most patients who discontinue short-term experience rapid weight regain rather than metabolic damage, which is why sustained therapy typically produces better long-term outcomes

It is a triple hormone receptor agonist that targets GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors

Patients should only obtain drugs containing semaglutide with a prescription from a licensed health care provider, and only obtain medicines from state-licensed pharmacies or outsourcing facilities registered with FDA. The Alliance for Pharmacy Compounding issued a statement on semaglutide last week in which it advised consumers not to shop online for anything purported to be semaglutide if they dont have a prescription and cant verify that the seller is a licensed US pharmacy

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Retatrutide and semaglutide are two drugs that look to initiate this metabolic transformation