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A systematic review and meta-analysis of 12 randomized controlled trials (RCTs) involving 11 459 overweight or obese adults without diabetes demonstrated that GLP-1 receptor agonists significantly reduced body weight, alongside notable improvements in glycemic control, lipid levels, and blood pressure

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1 2 Sharma MK, Jalewa J, Hlscher C (February 2014)

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These observations suggest that omnivorous individuals represent an appropriate study population for investigating interventions to reduce TMAO production

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