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This is a fundamentally different approach than pharmaceutical GLP-1 agonists, which bypass the gut entirely and activate receptors directly
10.1093/ajcn/68.3.525 12
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Some researchers have explored doses at the initial titration level (for example, 0.25 mg weekly of semaglutide, which is the standard starting dose for Ozempic but subtherapeutic for glycemic control), hypothesizing that anti-inflammatory benefits might be achieved with reduced gastrointestinal side effects
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