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Large-scale, randomised controlled trials specifically designed to assess acne as a primary outcome of B12 supplementation are lacking
Legality varies by jurisdiction and intended use
In more rare yet severe cases, you may experience: Itching or a feeling of swelling all over the body Muscle cramps and weakness Upset stomach and urinary problems Swelling in the ankles or feet Unusual tiredness Irregular heartbeat or trouble breathing If these side effects occur, consult your healthcare provider before continuing B12/MIC
No Human Adverse-Event Programme Without a controlled clinical development programme, the frequency and severity of possible adverse reactions cannot be estimated reliably
If a patient requires more than 1000 mcg in a single session, which is uncommon in standard practice, discuss with your MAC before billing multiple units
This can be due to having low levels of intrinsic factor in the digestive system, having a digestive condition, or following a plant-based diet
