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98 In obese subjects, 36 weeks of orforglipron therapy produced a dose-dependent weight loss of up to 14.7%, compared to 2.3% in the placebo group, accompanied by favorable changes in cardiometabolic risk factors
(4) Subgroup analyses provided further insights into the heterogeneity of associations observed among GLP-1 RA Users, highlighting age-, sex-, and comorbidity-related differences in both mortality and the composite pancreatitis outcome
Drugs were administered for 6 months
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Drucker, J.J
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