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Glucagon-like peptide-1 receptor agonist exendin-4 mitigates lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages
Therapeutic levels of glutathione in blood are difficult to arrive at since glutathione, especially GSH, exists in the serum as well as erythrocytes and leucocytes
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[5] This rapid breakdown explains why therapeutic GLP-1 receptor agonists have been chemically modified to resist DPP-4 degradation, thereby extending their duration of action and clinical efficacy in managing diabetes and obesity
