Vitamin D-abhängige Rachitis, Typ IA Einzelanalyse With frequent heavy bleedings

With frequent heavy bleedings

Mutation: AGXT gene

The condition is caused by complete absence of fibrinogen

generalized muscle atrophy and cardiomyopathy is observed in the English Springer Spaniels

The dilution of black pigment results in blue or grey coat colour

Vitamin D-abhängige Rachitis, Typ IA Einzelanalyse With frequent heavy bleedingsVitamin D deficiency rickets, type IA is an autosomal recessive disorder of bone development in young, growing dogs because of deficiency of vitamin D. The resultant active form of vitamin D is a steroid hormone that plays a vital role in whole body calcium homeostasis. The clinical signs of rickets arise from low serum calcium, failure of calcification of bones, leading to bone deformities, such as bowing of limbs, delayed dentition, lameness and