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Hypomyelinisierung / Shaking Puppy Syndrome (SPS) Hunde Cataract is one of the

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Description

Cataract is one of the most common hereditary problems in Australian Shepherds and certainly the most common heritable eye disease of this breed

der ein wichtiger Vermittler in der Signaltransduktion in Netzhautrezeptoren ist

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verursacht durch eine Störung der Signalübertragung an der neuromuskulären Verbindung

It is controlled by heterozygous mutations of merle locus and a modifier harlequin locus

Hypomyelinisierung / Shaking Puppy Syndrome (SPS) Hunde Cataract is one of theShaking puppy syndrome (SPS) or hypomyelination syndrome (HS) is a disease characterized by an abnormally low amount of myelination or its absence in the axons of the central nervous system (CNS). SPS has been described in people and in dogs including Dalmatian, Bernese Mountain dog, Chow Chow and Weimaraner breeds. The cause of SPS is not known in all breeds. A causative mutation in the gene in Weimaraner breeds has been reported. In Weimaraner

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