Faktor VII Defizienz (FVII) Mischling the disease develops before 4

the disease develops before 4 months of age and might progress slowly

DLA haplotype determination as an additional evaluation

Abnormal discs are predisposed to herniation leading to IVDD in dogs at young age

There is a 50% probability to transfer the 'cocoa' allele to the offspring

meaning that the most dominant allele present will be expressed

Faktor VII Defizienz (FVII) Mischling the disease develops before 4Factor VII (FVII) is a vitamin K dependent coagulation factor. It is synthesized in the liver and secreted into the circulation. It plays a major role in initiation of blood coagulation. Factor VII deficiency is associated with a bleeding tendency. Clinical signs in affected dogs include mild to severe bleeding after trauma or surgery. Inheritance: autosomal recessive Mutation: Coagulation factor VII gene Genetic test: The method used for testing is