Nemaline Myopathie (NM) DogCheck Ay allele is the most

Ay allele is the most dominant allele and determines the fawn or sable coat colour

It allows expression of A-Locus

Die betroffenen Hunde zeigen keine anderen klinischen Symptome

L-2-Hydroxyglutarazidurie (L-2-HGA) ist eine neurometabolische Störung

The disease primarily affects photoreceptors initially

Nemaline Myopathie (NM) DogCheck Ay allele is the mostNemaline myopathy is a congenital muscle disorder that affects both humans and dogs. The disease is characterized by the presence of rod bodies in the skeletal muscle fibres, non progressive generalized muscle weakness, exercise intolerance, tremors and hypotonia (decreased muscle tone). The disease is typically first observed when puppies are around 2 months old. At this stage, the puppies can move but have generalized muscle atrophy and tremors