Alexander Krankheit Hundebesitzer-Featured Mutation: VDR gene

Mutation: VDR gene

das Risiko frühzeitig zu erkennen und gezielt Vorsorgemaßnahmen zu treffen

zwischen verschiedenen Formen und Details von Objekten in einer bestimmten Entfernung zu unterscheiden

opaque corneas

along with paroxysmal neurological episodes consisting of head tremors and involuntary movements of one of the front limbs

Alexander Krankheit Hundebesitzer-Featured Mutation: VDR geneAlexander disease is a progressive fatal neurodegenerative hereditary disorder, caused by astrocyte dysfunction. Astrocytes are specialized cells in the brain and spinal cord, which contain a specific protein called glial fibrillary acidic protein (GFAP). Mutation in GFAP gene is the most common cause of the disease. The age of affected dogs is usually less than 12 months. Clinical signs begin as incoordination, a head tilt, knuckling on limbs, issues